Tion and migration of embryonic neural stem cells at low O2 levels. J Bio Chem 2011, 286(20):17649?7657. 10. Karow M, Popp T, Egea V, Ries C, Jochum M, Neth P: Wnt signaling in muse mesenchymal stem cells: influence on proliferation, invasion and MMP expression. J Cell Mol Med 2009, 13(88):2506?520. 11. Bendardaf R, Buhmeida A, Hilska M, Laato M, Syrj en S, Syrj en K, Collan Y, Pyrh en S: MMP-9 (gelatinase B) expression is linked with disease-free survival and disease-specific survival in colorectal cancer individuals. Cancer Invest 2010, 28(1):38?three. 12. Lee MA, Park KS, Lee HJ, Jung JH, Kang JH, Hong YS, Lee KS, Kim DG, Kim SN: Survivin expression and its clinical significance in pancreatic cancer. BMC Cancer 2005, five:127?32. 13. Neth P, Ciccarella M, Egea V, Hoelters J, Jochum M, Ries C: Wnt signaling regulates the invasion capacity of human mesenchymal stem cells. Stem Cells 2006, 24(eight):1892?903. 14. Elzagheid A, Buhmeida A, Korkeila E, Collan Y, Syrjanen K, Pyrhonen S: Nuclear beta-catenin expression as a prognostic factor in sophisticated colorectal carcinoma. Globe J Gastroenterol 2008, 14(24):3866?871. 15. Suzuki H, Masuda N, Shimura T, Araki K, Kobayashi T, Tsutsumi S, Asao T, Kuwano H: Nuclear beta-catenin expression in the invasive front and within the vessels predicts liver metastasis in colorectal carcinoma. Anticancer Res 2008, 28(3B):1821?830. 16. Kahlil S, Tan GA, Giri DD, Zou XK, Howe LR: Activation status of Wnt/catenin signaling in typical and neoplastic breast tissues: connection to HER2/neu expression in human and mouse. PLos A single 2012, 7(three):e33421. 17. Moyes LH, McEwan H, Radulescu S, Pawlikowski J, Lamm CG, Nixon C, Sansom OJ, Going JJ, Fullarton GM, Adams PD: Activation of Wnt signalling promotes development of dysplasia in Barrett’s oesophagus.Sulfinyldibenzene site J Pathol 2012, 228(1):99?12. 18. Voloshanenko O, Erdmann G, Dubashi TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Ken G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M: Wnt secretion is necessary to keep higher levels of wnt activity in colon cancer cells. Nat Commun 2013, 4:2610. 19. Cheung LW, Leung Pc, Wong AS: Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness via c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9. Cancer Res 2006, 66(22):10902?0910.Lee et al. BMC Cancer 2014, 14:125 http://biomedcentral/1471-2407/14/Page 7 of20. Roh SA, Choi EY, Cho DH, Jang SJ, Kim SY, Kim YS, Kim JC: Growth and invasion of sporadic colorectal adenocarcinomas in terms of genetic alter.DBCO-acid Chemical name J Korean Med Sci 2010, 25:353?60.PMID:24059181 21. Song KS, Li G, Kim JS, Jing K, Kim TD, Kim JP, Search engine optimisation SB, Yoo JK, Park HD, Hwang BD, Lim K, Yoon WH: Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/-catenin in SW480 human colon cancer cells. BMC Cancer 2011, 11:307. 22. Singh T, Katiyar SK: Honokiol Inhibits Non-Small Cell Lung Cancer Cell Migration by Targeting PGE2-Mediated Activation of -Catenin Signaling. PLos A single 2013, 8(three):e60749. 23. Naik S, Dotharger RS, Marasa J, Lewis CL, Piwnica-Worms D: Vascular endothelial growth element receptor-1 is synthetic lethal to aberrant beta catenin activation in colon cancer. Clin Cancer Res 2009, 15(24):7529?537. 24. Zeitlin BD, Ellis LM, Nor JE: Inhibition of vascular endothelial growth element receptor-1/wnt beta catenin cross talk results in tumor cell death. Clin Cancer Res 2009, 15(24):7453?455. 25. Yoshih.