Emographical qualities Mean age SD in years Male sex, n ( ) Pesticide exposure Suicidal, n ( ) Prehospitalization period median (IQR) in hours Patient clinical characteristics (n ( )) Vomiting Oral ulcers Throat discomfort Abdominal pain Dysphagia Dyspnea Comorbid illness Psychiatric illness, n ( )SD = Typical deviation, IQR = Interquartile rangeObjectivesIn the present study we aimed to study the demographics of patient, clinical characteristics and therapy pattern for herbicide poisoning in tertiary care hospital.25.38?.136 36 (60) 57 (95.0) 3.50 (9.25) 41 (68.three) 19 (31.7) 16 (26.7) 14 (23.3) 10 (16.7) 6 (10.0) 4 (6.7)Materials AND METHODSA retrospective observational study was carried out on patients with herbicide poisoning admitted in emergency ward of tertiary care Hospital in South India in between January 2004-2012. Sixty patients have been integrated within the study. A detailed history had been taken from the patient records of health-related record section. Demographic characteristics like age, sex, kind of exposure, pre-hospitalization period, clinical features, type of compound in addition to therapy and outcome had been obtained from the patient files. These had been recorded utilizing standardized data collection types and had been analyzed working with SPSS 16.0 package.Table 2: Percentage of diverse herbicide poisoningHerbicide compound Paraquat Glyphospate Frequency ( ) 47 (78.3) 13 (21.7)RESULTSDuring the study period, 60 individuals of Herbicide poisoning have been admitted towards the emergency ward of tertiary care Hospital in South India. Gender sensible distribution showed that majority of them had been males which constitute 60 in the study population. There have been 36 male and 24 female individuals plus the male/female ratio was almost 3:two. The median age of the study population was identified to become 25.38 ?9.136 yrs. Majority of poisoning wereTable 3: Occupation and Herbicide poisoningOccupation Student Farmer Coolie Business enterprise Others Frequency of poisoning ( ) 15 (25.0) 12 (20.0) five (8.three) 2 (3.three) 26 (43.3)Toxicology International May-Aug 2014 / Vol-21 / Issue-Cherukuri, et al.: Management of herbicide poisoninghemoperfusion was carried out only in four (6.7 ). The outcome evaluation of herbicide poisoning circumstances admitted through study period, 23 (38.3 ) of them recovered, 37 (61.7 ) of them have been expired. Facts regarding treatment and outcome are provided in Table 4.phosphide.[13] In pesticide poisoning the fatality rate is amongst 18 and 23 with highest fatality rates in case of paraquat.[14-17] Inside the present study majority of the herbicide poisonings have been as a consequence of deliberate self-harm (95 ) with higher mortality rate 61.2-Bromo-6-iodoaniline Formula 7 .Methyl 1H-imidazole-5-carboxylate supplier The frequent clinical options of herbicide poisoning as observed in our study are as follows: Vomiting (68.PMID:23819239 3 ), oral ulcers (31.7 ), throat discomfort (26.7 ), abdominal discomfort (23.3 ), dysphagia (16.7 ) and dyspnea (ten ). As per study performed by Sandhu et al., 2003 the frequent symptoms for paraquat poisoning were vomiting (100 ) followed by oral ulceration (59 ), dysphagia (53 ) and dyspnea (41 ).[18] For glyphosate poisoning the clinical manifestations incorporate corrosive effects around the gastrointestinal tract, Tachy- and brady-arrhythmias, renal failure, elevated liver enzymes, hyperkalemia and metabolic acidosis.[19] Out of 60 patients 4 (six.7 ) individuals had psychiatric illness. It is certainly one of the threat aspect for the intentional self-harm. According Eddleston and Phillips psychiatric illness is definitely the among the main risk aspect for self-poisoning. By prophylactic healthcare managemen.